Spasmonac® PT4

Brand Name: Spasmonac® PT4

Composition: Aceclofenac 100mg + Paracetamol 325mg + Thiocolchicoside 4mg Tablets

Mechanism of action (MOA)

  1. Aceclofenac: Preferential COX-2 inhibitor with potent anti-inflammatory and analgesic properties.
  2. Paracetamol: acting analgesic that elevates pain threshold.
  3. Thiocolchicoside: A centrally acting muscle relaxant that modulates GABA-A receptors to relieve muscle spasm.
  4. Synergistic Efficacy: Triple therapy demonstrated significant improvement in pain and mobility in acute low back pain, with 70% of patients rated as having “excellent” efficacy.

Indications

  1. Acute lower back pain with muscle spasm
  2. Neck Pain and Cervical Spondylosis
  3. Postoperative Musculoskeletal Pain
  4. OA flare with muscle spasm

References

  1. Arslan, S. Akkus, and Figen Tirnaksiz. "A nonsteroidal anti-inflammatory drug: Aceclofenac.
  2. Anderson, Brian J. "Paracetamol (Acetaminophen): mechanisms of action." 18.10 (2008): 915-921.
  3. Kamath, Ashwin. "Thiocolchicoside: a review." DHR Int J Med Sci 4.2 (2013): 39-45.
  4. Lahoti G. J Indian Med Assoc. 2012;110(1):56–58

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