Pzokin^® DSR

Brand Name: Pzokin^® DSR

Composition: Pantoprazole 40mg (EC) + Domperidone 30mg (SR) Capsules

Mechanism of action (MOA)

1. ensures sustained acid suppression via selective PPI; Domperidone enhances upper GI motility via peripheral D₂ antagonism
2. The combination targets both acid and motility-related symptoms effectively

Indications

1. Gastroesophageal Reflux Disease (GERD)
2. Functional Dyspepsia
3. Peptic Ulcer Disease
4. Prevention of NSAID-Induced Gastropathy

References

1. Robinson M, Horn J. Clinical pharmacology of proton pump inhibitors
2. Camilleri M. Clinical pharmacology of gastrointestinal prokinetic agents. Clin Pharmacokinet.
3. Bharucha AE, Camilleri M. The efficacy of domperidone for chronic dyspepsia and gastroparesis. Am J Gastroenterol.